Infection by HPV in the oral cavity - A literature review

Autores

  • Luciana Barros Augé Mestranda no curso de Mestrado em Ciências da Saúde e da Vida, da Universidade Franciscana
  • Bruno Martinazzo Bier Acadêmico do curso de Medicina da Universidade Franciscana, UFN, Santa Maria, RS. https://orcid.org/0000-0002-2433-1037
  • Paula Köhler Carpilovsky Acadêmica do curso de Medicina da Universidade Franciscana, UFN, Santa Maria, RS.
  • Cristiane Köhler Carpilovsky Departamento de Morfologia da Universidade Federal de Santa Maria, RS. http://orcid.org/0000-0001-9712-3741
  • Luciana Maria Fontanari Krause Professora/orientadora do curso de Mestrado em Ciências da Saúde e da Vida, Universidade Franciscana, UFN, Santa Maria, RS. http://orcid.org/0000-0001-8294-2533

Resumo

Human papillomavirus (HPV) is a microorganism that has the potential to infect the skin and mucous membranes, causing local tissue injury or remaining asymptomatic. When one’s immune system is not capable of fighting an invasion of the virus, it remains latent inside the nucleus of infected cells. One of the clinical manifestations is the presence of benign epithelial lesions in the oral cavity, which include squamous cell papilloma, common skin warts, focal epithelial hyperplasia and papillary hyperplasia. Human papillomaviruses have an etiological role in cancers of the pharynx and the oral cavity, with 25-50% of cases being attributed to HPV infections. A literature review was carried out in big contemporary databases and included papers from any year of publishing, going back as far as reviewing the history of its viral taxonomic classification all the way to current clinical approaches and therapies to patients with this infection, as well as immunization strategies with vaccines. It has been observed that the development of oropharyngeal cancer in a younger and non-smoking population could be attributable to HPV as an independent causal factor and has been a subject of increasing interest for the research community. HPV vaccination is expected to impact oral HPV incidence rates, leastwise for the genotypes included in the vaccine.

Biografia do Autor

Luciana Barros Augé, Mestranda no curso de Mestrado em Ciências da Saúde e da Vida, da Universidade Franciscana

Ciências da Saúde

Bruno Martinazzo Bier, Acadêmico do curso de Medicina da Universidade Franciscana, UFN, Santa Maria, RS.

Ciências da Saúde

Paula Köhler Carpilovsky, Acadêmica do curso de Medicina da Universidade Franciscana, UFN, Santa Maria, RS.

Ciências da Saúde

Cristiane Köhler Carpilovsky, Departamento de Morfologia da Universidade Federal de Santa Maria, RS.

Departamento de Morfologia, UFMS, Santa Maria, RS.

Luciana Maria Fontanari Krause, Professora/orientadora do curso de Mestrado em Ciências da Saúde e da Vida, Universidade Franciscana, UFN, Santa Maria, RS.

Ciências da Saúde

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Publicado

2021-01-21

Como Citar

Augé, L. B., Bier, B. M., Carpilovsky, P. K., Carpilovsky, C. K., & Krause, L. M. F. (2021). Infection by HPV in the oral cavity - A literature review. Disciplinarum Scientia | Saúde, 21(3), 45–64. Recuperado de https://periodicos.ufn.edu.br/index.php/disciplinarumS/article/view/3485

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