Microalgae oil and vitamin E: from nanostructuring to safety profile

Authors

  • Elisandra da Silva Pena da Fonseca Universidade Franciscana
  • Walter Paixão de Sousa Filho Universidade Franciscana
  • Rodrigo de Almeida Vaucher Universidade Federal de Pelotas
  • Diego de Souza Universidade Franciscana
  • Michele Rorato Sagrillo Universidade Franciscana
  • Liana da Silva Fernandes Universidade Franciscana https://orcid.org/0000-0003-4745-7617

DOI:

https://doi.org/10.37779/nt.v23i2.4183

Abstract

In the last few years, nanotechnology seeks to expand its nanocarrier systems, to increasingly ensure that the incorporated assets maintain their properties and benefits with greater efficiency and safety. Thus, nanoencapsulation has been widely used, mainly in the cosmetic industry, which aims to combine new technologies in its products that guarantee good efficacy of the active principles used in conjunction with renewable and sustainable natural bioactive. In this context, the objective of this study was to nanoencapsulate the oil extracted from the microalgae Chlorella homosphaera with the addition of the vitamin E, to guarantee the properties and stability of this oil and the vitamin, facing encapsulation. Then, evaluate the biocompatibility of the nanocapsules for a possible topical use formulation. Nanocapsules containing microalgae oil and vitamin E were produced by the nanoprecipitation method and then physically chemically characterized, after cytogenotoxicity and hemocompatibility tests with the nanoformulations were performed to assess the safety profile of the formulations. The nanocapsules showed satisfactory results, such as average particle diameter, polydispersion index, zeta potential, and pH with values within the expected limits for the formulation produced and did not show cytotoxicity in the tests performed. Concluding that nanoencapsulation is a possible alternative for using oil from the microalgal origin with vitamin E for cosmetic formulations and topical use.

Author Biographies

Elisandra da Silva Pena da Fonseca, Universidade Franciscana

Mestre em Nanociências.

Walter Paixão de Sousa Filho, Universidade Franciscana

Mestre em Nanociências.

Rodrigo de Almeida Vaucher, Universidade Federal de Pelotas

Docente da UFPEL.

Diego de Souza, Universidade Franciscana

Pós-doutorando Programa de Pós-Graduação em Nanociências.

Michele Rorato Sagrillo, Universidade Franciscana

Docente do Programa de Pós-Graduação em Nanociências na UFN.

Liana da Silva Fernandes, Universidade Franciscana

Docente do Programa de Pós-Graduação em Nanoiências na UFN.

Published

2022-06-10

How to Cite

da Fonseca, E. da S. P., de Sousa Filho, W. P., Vaucher, R. de A., de Souza, D., Sagrillo, M. R., & Fernandes, L. da S. (2022). Microalgae oil and vitamin E: from nanostructuring to safety profile. Disciplinarum Scientia | Naturais E Tecnológicas, 23(2), 19–38. https://doi.org/10.37779/nt.v23i2.4183

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Artigos