Differential gene expression and pathways associated with the angiogenesis in esophageal nasopharyngeal cancer

Abstract

Cancer is a disease caused by molecular disorders associated to the mechanisms by which cell division is controlled. In this sense, diseases were analyzed with the purpose of clarify the molecular pathways behavior and mechanisms associated with genome stability in cancer. The goal this study was to better elucidate the role of angiogenesis pathways in esophageal and nasopharyngeal cancer using quantitative methods to determine gene expression, activity and relative diversity. The results obtained suggested that the enzymes of the matrix metalloproteinases family are associated with the development and progression of cancer in relation to esophageal and Nasopharynx. These findings may contribute to improve the elucidation of the mechanisms associated with the angiogenesis in the evolution and differentiation in cancer cases considered by us.